Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea

  • Saravana Kumar.K Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India
  • Chandra Sekhar K.B Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Anantapur - 515 002, Andhra Pra-desh, India
  • Jayachandra Reddy.P Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati, Chittoor District - 517 506, Andhra Pradesh, India
  • Grace Rathnam Department of Pharmaceutics, C.L. Baid Metha College of Pharmacy, Jyothi Nagar, Old Mahabalipuram Road, Thorapakkam, Chennai - 600 096, India
  • Sankari.E Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India
  • Nagaveni.P Seshachala College of Pharmacy, Tirupati Chennai Highway, Puttur, Chittoor Dist. – 517583, Andhra Pradesh, India

Abstract

The Cause of fever in patients is mainly due to, when the body’s immune response is triggered by pyrogens (fever – producing substances). Pyrogens usually come from a source outside the body and in turn, stimulate the production of pyrogens inside the body. The plant is reported to contain coumarins, falvonoids, carotenoids, flavanones, iso-flavanones and quercetin. The plant has been reported to have anti-pyretic, anti-helmintic, hepato-protective, anti-ulcer, anti-inflammatory, antimicrobial properties. The methanolic extract of Tephrosia Purpurea leaves was investigated for its anti-pyretic activity. Anti-pyretic potential of methanolic extract was evaluated by Brewer’s yeast induced pyrexia test. The pyrexia in rats was reduced significantly (P<0.01) compared to that of control.

Keywords: Pyrogens, Methanolic extract, Anti-Pyretic activity, Pyrexia, Brewer’s yeast

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Published
2011-10-20
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How to Cite
Saravana Kumar.K, Chandra Sekhar K.B, Jayachandra Reddy.P, Grace Rathnam, Sankari.E, & Nagaveni.P. (2011). Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea. International Journal of Research in Pharmaceutical Sciences, 2(4), 688-691. Retrieved from https://pharmascope.org/index.php/ijrps/article/view/986
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Original Articles
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