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The Cause of fever in patients is mainly due to, when the body’s immune response is triggered by pyrogens (fever – producing substances). Pyrogens usually come from a source outside the body and in turn, stimulate the production of pyrogens inside the body. The plant is reported to contain coumarins, falvonoids, carotenoids, flavanones, iso-flavanones and quercetin. The plant has been reported to have anti-pyretic, anti-helmintic, hepato-protective, anti-ulcer, anti-inflammatory, antimicrobial properties. The methanolic extract of Tephrosia Purpurea leaves was investigated for its anti-pyretic activity. Anti-pyretic potential of methanolic extract was evaluated by Brewer’s yeast induced pyrexia test. The pyrexia in rats was reduced significantly (P<0.01) compared to that of control.


Pyrogens Methanolic extract Anti-Pyretic activity Pyrexia Brewer’s yeast

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How to Cite
Saravana Kumar.K, Chandra Sekhar K.B, Jayachandra Reddy.P, Grace Rathnam, Sankari.E, & Nagaveni.P. (2011). Elucidation of pharmacognostic profiles and pharmacological activity of Tephrosia Purpurea. International Journal of Research in Pharmaceutical Sciences, 2(4), 688-691. Retrieved from