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Anti-inflammatory activity of the methanolic extracts of the root of Indigofera oblongifolia Forsk was studied in Wistar rats using the carrageenan induced left hind paw edema. The methanolic extracts at the dose of 250 mg/kg and 500 mg/kg body weight shows moderate to significant anti-inflammatory activity. The methanolic extracts of Indigofera oblongifolia Forsk reduced the edema induced by carrageenan by 32.19 % and 40.97 % respectively on oral administration of 250 mg/kg and 500 mg/kg body weight as compared to the untreated control group. Diclofenac sodium at 10 mg/kg body weight inhibited the edema volume by 39.02 %. The results indicated that the methanolic extract 500 mg/kg body weight shows more significant (p<0.05) anti-inflammatory activity when compared with the standard and untreated control.
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