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The various leaves extracts such as ethanol, chloroform and petroleum ether: ethanol (1:1) of Vanda coerulea Griff. ex Lindl. were investigated for an in vitro antibacterial activity by disc diffusion method . Ethanolic leaf extracts produced definite antibacterial activity against gram positive Bacillus cereus than Streptococcus faecalis, Streptococcus pneumonia and Staphylococcus aureus and very less inhibition by gram negative bacteria such as E. coli and Salmonella typhi. The present study reveals that the ethanolic extracts of Vanda coerulea leaf had more antibacterial activity against all bacteria tested followed by chloroform and petroleum ether: ethanol (1:1) extracts. From the present study, it reveals that the selected plant material has potential antibacterial activity against gram positive bacteria Bacillus cereus.
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