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Avocado fruits are very popular among vegetarians as an excellent substitute for meats in sandwiches and salads in some countries because of its high fat content. It is also one of the common fruits in the state of Mizoram, India. Though the fruit is loaded with various nutrients, leaves are toxic. The study deals with biochemical and gross pathological changes associated with avocado leaves poisoning in rabbits. Serum enzymes, SGOT and SGPT were found to be elevated accompanied by the changes in concentration of sodium, phosphorus and chloride. Such biochemical changes can be correlated with the gross pathologic observation in various organs which includes fluid filled pericardium, congested and necrotic liver and detachment of stomach mucosal layer exposing the red congested submucosal layer.
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