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Abstract

Coronary artery disease (CAD) is a spectrum of heart diseases which has the highest mortality in the world. Systolic left ventricular (LV) function is an important predictor of outcome, and its precise assessment remains of great importance for the choice of treatment in populations with myocardial infarction (MI). This study was aimed to assess the function and viability of ischemic myocardium of LV before and after the percutaneous coronary intervention (PCI) by using 2dimentional (2D) STE with LDDSE and to know the usefulness of low dose dobutamine (LDD) test in detecting the viable ischemic LV area. The results of the current study revealed there was a significant decrease (improvement) in GLS before dobutamine from (-10.49±3.4) to (-12.87±3.44) after dobutamine. Then there was a significant increase (deterioration) in GLS from (-12.87±3.44) after giving 5 mg/kg/min dobutamine to (-11.56±3.29) after giving 10 mg/kg/min dobutamine (P value < 0.001). While there were no significant differences in GLS after low dose dobutamine (-12.87±3.44) with the same parameters 3-6 months after PCI (-13.48±3.7). Left anterior descending artery (LAD) is the most common affected artery in our study. The study concluded that GLS provides a sensitive measure of LV function and appears reduced despite preserved LVEF also GLS can detect the viability of ischemic myocardium of LV with using LDD test which then assessed by PCI.

Keywords

Left ventricle Speckle tracking echocardiography Dobutamine stress echocardiography Global longitudinal strain Ejection fraction Percutaneous coronary intervention

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How to Cite
Reem Jamal Jabir, Affan Ezzat Hasan, Qasim Mohammed Jumaah, & Layth Rafea Taqa. (2019). Evaluation of patients with myocardial infarction undergoing percutaneous coronary intervention (PCI) using low dose dobutamine stress echocardiography. International Journal of Research in Pharmaceutical Sciences, 10(2), 1516-1522. https://doi.org/10.26452/ijrps.v10i2.781