Accelerated stability study and quantitative estimation of piperine in Draksharishta

  • Vaibhav Tiwari1 Ayurvedic Pharmacy Research Laboratory, Rajiv Gandhi South Campus, Banaras Hindu University, Mirzapur–231001, Uttar Pradesh, India
  • Kumar B.M.N Department of Sharir Rachana, Rajiv Gandhi South Campus, Banaras Hindu University, Mirzapur–231001, Uttar Pra-desh, India
  • Vineet Sharma Department of Rasa Shastra, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005 Uttar Pradesh, India
  • Dev Nath Singh Gautam Department of Rasa Shastra, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005 Uttar Pradesh, India

Abstract

The objective of the present study was to evaluate the accelerated stability study and estimation of piperine from Draksharishta. Accelerated stability study was done for 6 months to distinguish the stability of polyherbal formulation in reference to its physicochemical, phytoconstituents within. Asava and Arishta are self-generated herbal fermentations of traditional ayurvedic system. Draksharishta was prepared as per AFI part-1(The Ayurvedic formulary of India, part-1) using authenticated raw drugs. For accelerated stability study for six months period the prepared sample of Draksharishta was placed in the controlled situation following ICH (International Conference on Harmonization) guidelines. The intermediate sampling was done at initial, after 1, 3 and 6 months respectively. The organoleptic characters and physicochemical parameters of samples showed similar results to that sample at starting the month; it indicates that product was stable and having required stability. No significant variations in the value of alcohol content, acidity and sugar content of sample had been reported over 6-month storage. An only significant variation in the value of total phenolic content was observed. On the basis of this stability study, it could be said that this formulation was stable for the period of more than 24 months on the basis of arrhenius equation.

Keywords: Accelerated Stability, Arishta, Draksharishta, Piperine

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Published
2017-04-14
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How to Cite
Vaibhav Tiwari1, Kumar B.M.N, Vineet Sharma, & Dev Nath Singh Gautam. (2017). Accelerated stability study and quantitative estimation of piperine in Draksharishta. International Journal of Research in Pharmaceutical Sciences, 8(2), 214-220. Retrieved from https://pharmascope.org/index.php/ijrps/article/view/591
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