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The objective of the present study was to evaluate the accelerated stability study and estimation of piperine from Draksharishta. Accelerated stability study was done for 6 months to distinguish the stability of polyherbal formulation in reference to its physicochemical, phytoconstituents within. Asava and Arishta are self-generated herbal fermentations of traditional ayurvedic system. Draksharishta was prepared as per AFI part-1(The Ayurvedic formulary of India, part-1) using authenticated raw drugs. For accelerated stability study for six months period the prepared sample of Draksharishta was placed in the controlled situation following ICH (International Conference on Harmonization) guidelines. The intermediate sampling was done at initial, after 1, 3 and 6 months respectively. The organoleptic characters and physicochemical parameters of samples showed similar results to that sample at starting the month; it indicates that product was stable and having required stability. No significant variations in the value of alcohol content, acidity and sugar content of sample had been reported over 6-month storage. An only significant variation in the value of total phenolic content was observed. On the basis of this stability study, it could be said that this formulation was stable for the period of more than 24 months on the basis of arrhenius equation.
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