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Abstract

Removal of Pregabalin from aqueous solution as well as industrial effluent using a new, efficient and cost-effective activated carbon derived from groundnut seed cake powder (GNSCP) and coconut cake powder (CCP) has been presented in this study. Experimentation has been carried out by optimizing various parameters such as pH, contact time, dosage, temperature and initial drug concentration using a batch adsorption model. Surface texture and morphology of the activated carbons have been analyzed by HR SEM; Characterization of the adsorbents has been carried out using FTIR and PXRD. Bio-sorption of Pregabalin using GNSCP and CCP followed pseudo-second-order kinetics. Langmuir adsorption isotherm suits the best for the present study. Thermodynamic studies showed that the adsorption of the drug onto the chosen adsorbents is a spontaneous and feasible process. The maximum adsorption capacity for the uptake of Pregabalin by GNSCP was found to be 9.71 mg/g and with CCP 9.83 mg/g. Suitability of the adsorbents for the treatment of industrial effluent has also been carried out and found to have 98 % removal of the drug from the effluent.

Keywords

Bio-sorption Coconut cake powder Freundlich isotherm Groundnut seed cake powder Langmuir isotherms Pregabalin Pseudo second order kinetics Temkin isotherm

Article Details

How to Cite
Chandrarao D, Rama Devi D, Vani P, Basavaiah K, Satyabalaji T, & Narasimha Raju Ch.B.V. (2021). Byproducts from the edible oil industry as potential adsorbent for the removal of Pregabalin from aqueous solution. International Journal of Research in Pharmaceutical Sciences, 12(2), 1513-1520. https://doi.org/10.26452/ijrps.v12i2.4730