Cytological and histopathological studies on the effect of honey in experi-mentally infected wounds in Wistar rats

  • Neeraja Rani Guruvu Department of Pharmacology, SIMATS, GEMS, Srikakulam, 532484 Andhra Pradesh India
  • Bandaru Narasinga Rao Department of Microbiology, Gayatri Vidya Parishad Institute of Health Care and Medical Technolo-gy, Marikavalasa, Madhurawada, Visakhapatnam – 530048 Andhra Pradesh, India
  • Vijayaraghavan R Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai -602105 Tamil Nadu, India
  • Sukumar E Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai -602105 Tamil Nadu, India
  • Senthilkumar Sivanesan Department of Research, Saveetha Institute of medial and technical science, Thandalam, Chennai -602105 Tamil Nadu, India

Abstract

Honey is used as food and home remedy in of India and other countries. Scientific studies have been carried out to support these properties of honey in this investigation, incision wounds of rats that were infected with three bacterial strains viz. Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, have been treated with honey and evaluated for its effect on days 1, 3, 6, 9 and 12 post-operatively with the help of smears and biopsies collected from lesions. Cytological and histopathological investigations of infected wounds conformed significant healing property of honey in and reduction in size.

Keywords: Wound healing activity, Infected wounds, Honey, Cytology, Histopathology, Wistar rats

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Published
2019-04-14
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How to Cite
Neeraja Rani Guruvu, Bandaru Narasinga Rao, Vijayaraghavan R, Sukumar E, & Senthilkumar Sivanesan. (2019). Cytological and histopathological studies on the effect of honey in experi-mentally infected wounds in Wistar rats. International Journal of Research in Pharmaceutical Sciences, 10(2), 1190-1195. https://doi.org/10.26452/ijrps.v10i2.405
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Original Articles
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