Pharmacovigilance study of the Penicillin's adverse drug reactions and their seriousness in the Iraqi hospitals

  • Ahmed Mohammed Ahmed Clinical Pharmacy Department, College of Pharmacy, University of Kufa, Baghdad, Iraq
  • Ahmed Hamed Jwaid Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad, Iraq
  • Manal M. Younus Head of Iraqi Pharmacovigilance Centre, Iraqi Ministry of Health, Baghdad, Iraq
  • Hayder A. Fawzi Clinical Pharmacy Department, Baghdad Medical City Hospital, Baghdad, Iraq

Abstract

Antibiotics represent one of the most prescribed drugs, antibiotics found to cause about 25% of the entirely reported Adverse Drug Reactions (ADRs), and the ADRs found to be one of the leading causes of morbidity and mortality worldwide. The data collected from the Iraqi Pharmacovigilance database then sorted and analysed, and eventually only 137 reports regarding penicillins included. The data showed that the Penicillins caused 48 severe ADRs and allergic reactions and skin responses were the most reported exceeding the half of the total pool of the ADRs. We concluded that the ADRs were mostly unpredictable or type B which unusual since it should not exceed the 20% of the total ADRs hence this is a new field of study in Iraq, further studies will be required to set the track of achieving the goal of pharmacovigilance.

Keywords: Adverse Drug Reactions, Allergic reactions, Antibiotics, Pharmacovigilance

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Published
2018-07-12
Citations
How to Cite
Ahmed Mohammed Ahmed, Ahmed Hamed Jwaid, Manal M. Younus, & Hayder A. Fawzi. (2018). Pharmacovigilance study of the Penicillin’s adverse drug reactions and their seriousness in the Iraqi hospitals. International Journal of Research in Pharmaceutical Sciences, 9(3), 1051-1055. Retrieved from https://pharmascope.org/index.php/ijrps/article/view/361
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Original Articles
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