Preparation of yeast mediated semiconductor nanoparticles by Candida albicans and its bactericidal potential against Salmonella typhi and Staphylococcus aureus

  • Venkat Kumar S School of Biosciences and Technology, VIT, Vellore – 632014, TN
  • Sowmya B School of Biosciences and Technology, VIT, Vellore – 632014, TN
  • Geetha R Department of Biochemistry, Arcot Sri Mahalakshmi women's college, Vilapakkam- 632521, TN
  • Karpagambigai S Departmant of Chemistry, Global Institute of Engineering and Technology, Vellore -632509, TN
  • Jacquline Rosy P Dept. of Chemistry, IFET College of Engineering, Villupuram-605108, TN
  • Rajeshkumar S Department of Pharmacology, Saveetha Dental College and Hospitals, SIMATS, Chennai – 600077, TN, India
  • Lakshmi T Department of Pharmacology, Saveetha Dental College and Hospitals, SIMATS, Chennai – 600077, TN, India

Abstract

Biosynthesis of nanoparticles using microorganism is widely used in biological applications due to its eco-friendly nature and lower cost. The present study aimed to investigate the yeast, Candida albicans for the synthesis of nano cadmium sulfide is a semiconductor nanoparticle. The yeast synthesized nanoparticles tested for its spectroscopic and microscopic characters. The peak at 420 nm identified by UV-Vis spectrophotometer confirms the Cadmium sulfide (CdS) nanoparticles synthesis preliminarily. Further, the nanoparticles were characterized using X-ray diffraction assay, scanning electron microscope, and elemental dispersive analysis. Finally, the synthesized Cadmium sulfide (CdS) nanoparticles were tested for its antibacterial activity against disease-causing pathogens such as Salmonella typhi and Staphylococcus aureus. The maximum zone of inhibition shows 15mm at the concentration of 100µl of CdS nanoparticle. Thus a promising antibacterial activity of yeast mediated synthesized Cadmium sulfide (CdS) nanoparticles was described.

Keywords: Semiconductor nanoparticles, Cadmium sulfide, Yeast, Antibacterial activity

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Published
2019-04-15
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How to Cite
Venkat Kumar S, Sowmya B, Geetha R, Karpagambigai S, Jacquline Rosy P, Rajeshkumar S, & Lakshmi T. (2019). Preparation of yeast mediated semiconductor nanoparticles by Candida albicans and its bactericidal potential against Salmonella typhi and Staphylococcus aureus . International Journal of Research in Pharmaceutical Sciences, 10(2), 861-864. https://doi.org/10.26452/ijrps.v10i2.262
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Original Articles
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