Synthesis and Biological Evaluation of Some Amides Compound Derivative of Oxezole Carboxylic Acids
In this present a new series of amidaes from 4, 5 di benzoic acid oxazole , 4-benzoic acid -5- phenel oxazole , 2-methyl 4 ,5 – di benzoic acid oxazole , 2-methyl-4 benzoic acid- 5-phenyl oxazole, 2-benzyl – 4.5 – di benzoic acid oxazole with aniline. The structure of the synthesized compounds was determined on the basis of them in fra-red tra, H- nuclear magnetic resonase and analysis elemental analysis spectral data and were tested for their antibacterial activity. The newly amides characterized by spectral IR table (2) spectral shown disappearance pf – cooh at 3500 cm and NH2 3320-3410 cm Absorption band in the other new derivative at (1770-1760) cm-1 to –C-NH) group of new amides because mesomeri effect and characterized by C-H-N and H NMR. In this study of the effect of the prepared compound in the two types of bacteria isolated from medical condition (human)(and it has studied and diagnosed and proved their attributes . it has identified its resistance of different antibiotic that are also carried out the development operations and increased the numbers of these bacteria in temperature (37C).
Article Level Metrics
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.