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Abstract

Phenytoin is an anticonvulsant and Hydantoin, it is mainly used in the management o Seizures, and it stabilizes the neuronal membranes and decreases seizure activity by increasing efflux or reducing the influx of sodium ions across cell membranes in the motor cortex during the generation of nerve impulses. It is available in the market in the form of oral and intravenous forms, a loading dose of Phenytoin for the management of seizures is 10-20 mg, divided into 2-3 doses. Stevens-Johnson syndrome is a rare and serious adverse effect of the skin along with the membranes of the mucous. It is caused by specific Drugs or Viral Infections. We have performed causality assessment by using the WHO and NARANJO'S ADR rating scale. It will seem, it is a Probable ADR, and severity assessed it confers a Type-A ADR, and it should be in Probably Preventable. So being a Reliable Clinical Pharmacist, we recommend to all health care professionals be aware of adverse drug reactions, and Desirable vigilance is necessitated toward safe and effective management for specific patients, strictly observe the patients in sequence anticipate Dangerous Adverse events.

Keywords

Phenytoin Steven Johnsons Syndrome 10 mg.36 Years Female WHO Scale Naranjo’s Scale Adverse Drug Reaction

Article Details

How to Cite
Naga Subrahmanyam S, Nagaraju G V, & Tagoore Vijaya Lakshmi D. (2020). Phenytoin induced Steven Johnson syndrome. International Journal of Research in Pharmaceutical Sciences, 11(1), 173-175. https://doi.org/10.26452/ijrps.v11i1.1803