Effect of an oat extract on oxidizing Stress and antioxidant defense in male rats with type 1 diabetes

  • Haidar Alsaedi Department of Basic Science, Faculty of Dentistry, Al-Qadisyah University, Iraq
  • Reem abdul Raheem Mirdan alsaad Department of anatomy and histology -College of medicine –university of Babylon, Iraq
  • Huda Raheem Hashim College of Basic Education - University of Al Muthanna, Iraq


The strong n-butanol extract of oats (Avena sativa) seed was studied in streptozotocin-induced diabetic rats to improve lipid peroxidation and inhibitor standing. Four teams, NDM, and three diabetic teams were allocated thirty-two male rats. Diabetes  was caused by injection- streptozotocin (60 mg / kg B.w., i.p. Two hundred mg/deal of blood sugar rodents was used as a diabetic. Diabetes groups (G2, G3, and G4) were trained to extract n-butanol (60 mg / metric unit weight, B.w.) or twenty-one days of endocrine injection (4 IU / animal). Weight gain was reported on the 22nd day. Fluids were collected for knockout cells to judge glucose concentrations and subcellular of aminotransferase, aspartate transaminase, catalase, biochemical dismutase (SOD), glutathione - transferase, reductase, malondialdehyde and glutathione reductase (Gr) concentrations. Diabetes rat (G2) showed a significant increase in glucose. The weight gain increased in the ALT, SOD, CAT, GSH-transferase But there decreased GSH enzyme and old AST. Treatment of N-butanol extract from oats (G3) or endocrine (G4) varied between old glucose, weight gain and normalization of all supermolecule inhibitors. Finally, n- Butanol from oatmeal has a strong role in lowering hyperglycemia and as an antioxidant

Keywords: Oat, antioxidant capacity, type 1 diabetes


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How to Cite
Haidar Alsaedi, Reem abdul Raheem Mirdan alsaad, & Huda Raheem Hashim. (2019). Effect of an oat extract on oxidizing Stress and antioxidant defense in male rats with type 1 diabetes. International Journal of Research in Pharmaceutical Sciences, 10(4), 3594-3599. https://doi.org/10.26452/ijrps.v10i4.1740
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