Phytochemical screened, characterization and antibacterial activity of hesperetin and hesperidin extracted and isolated from dried oranges peels

  • Bassam A. Hassan Depatment of Pharmaceutical Chemistry, College of Pharmacy, Thi-Qar University, Iraq
  • Fadil Mohsen Hamed Depatment of Pharmaceutical Chemistry, College of Pharmacy, Thi-Qar University, Iraq
  • Firas F. Alyaseen Department of Pharmacognosy, College of Pharmacy, Thi-Qar University, Iraq

Abstract

Oranges, fruits are bioactive citrus fruits belong to the Rutaceae, family. At the beginning of this study, Phytochemical screened of dried oranges peels showed the absence of coumarins, saponins, sterols, terpenoids, anthraquinones and protein. While the presence of flavonoids, alkaloids, carbohydrate, glycosides, tannins, polyphenol. Afterwards, Hesperetin (flavanone) and hesperidins (flavanone glycoside) were extracted and isolated from dried oranges peels (citrus fruits) and characterized by FTIR spectra, TLC, melting point, Chemical test. In time antibacterial activity of Hesperetin and hesperidins studied against some pathogenic bacterial strains isolated from patients like Streptococcus, Acinetobacter, E.coli, Klebsiella, Staphylococcus, Aeromonas. Eventually, Hesperetin (flavanone) showed a Higher biological activity significant than hesperidins and cefuroxime drugs.

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Published
2018-10-31
How to Cite
HASSAN, Bassam A.; HAMED, Fadil Mohsen; ALYASEEN, Firas F.. Phytochemical screened, characterization and antibacterial activity of hesperetin and hesperidin extracted and isolated from dried oranges peels. International Journal of Research in Pharmaceutical Sciences, [S.l.], v. 9, n. 4, p. 1362-1367, oct. 2018. ISSN 0975-7538. Available at: <https://pharmascope.org/index.php/ijrps/article/view/1685>. Date accessed: 13 dec. 2018. doi: https://doi.org/10.26452/ijrps.v9i4.1685.
Section
Original Articles
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