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Abstract

Olax scandensRoxb. (family Olacaceae) Available in throughout tropical India. The current study, aerial parts of different concentrates of Olax scandenswas evaluated for its in-vitro antioxidant potential by Diphenylpicrylhydrazyl activity, superoxide scavenging activity, iron chelating activity taking ascorbate,   quercetin & Ethylenediamine tetraacetate as the standard correspondingly. An IC50 value was originated that methanolic concentrates of Olax scandensis more efficient in Diphenylpicrylhydrazyl radical, superoxide radical activity, Iron chelating capacity compared EA & PE concentrates. The methanolic concentrates of Olax scandens & ascorbate exhibited antioxidant potential possessing IC50 226µg/ml & 66µg/ml (DPPH). 185µg/ml & 60µg/ml (Superoxide) , 287µg/ml & 65µg/ml (iron-chelating Activity) respectively. Invitro antioxidant studies obviously show methanolic concentrates of Olax scandens have better antioxidant activity. These results indicate that aerial parts of methanolic concentrates Olax scandenscould serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.

Keywords

Olax scandens DPPH radical scavenging Superoxide radical Iron chelating activity

Article Details

How to Cite
Pranaya P, & Akila Devi D. (2019). Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens. International Journal of Research in Pharmaceutical Sciences, 10(4), 3475-3480. https://doi.org/10.26452/ijrps.v10i4.1664