Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens

  • Pranaya P Sultan Ul Uloom College of Pharmacy, Hyderabad, India
  • Akila Devi D School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai, Tamil Nadu, India


Olax scandensRoxb. (family Olacaceae) Available in throughout tropical India. The current study, aerial parts of different concentrates of Olax scandenswas evaluated for its in-vitro antioxidant potential by Diphenylpicrylhydrazyl activity, superoxide scavenging activity, iron chelating activity taking ascorbate,   quercetin & Ethylenediamine tetraacetate as the standard correspondingly. An IC50 value was originated that methanolic concentrates of Olax scandensis more efficient in Diphenylpicrylhydrazyl radical, superoxide radical activity, Iron chelating capacity compared EA & PE concentrates. The methanolic concentrates of Olax scandens & ascorbate exhibited antioxidant potential possessing IC50 226µg/ml & 66µg/ml (DPPH). 185µg/ml & 60µg/ml (Superoxide) , 287µg/ml & 65µg/ml (iron-chelating Activity) respectively. Invitro antioxidant studies obviously show methanolic concentrates of Olax scandens have better antioxidant activity. These results indicate that aerial parts of methanolic concentrates Olax scandenscould serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.

Keywords: Olax scandens, DPPH radical scavenging, Superoxide radical, Iron chelating activity


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Pranaya P, & Akila Devi D. (2019). Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens. International Journal of Research in Pharmaceutical Sciences, 10(4), 3475-3480.
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