Effects of Nardostachys jatamansi extract on inflammatory and oxidative stress markers in hypertensive, hyperglycaemic patients: an open-label, prospective study

  • Rajyalakshmi I Department of Biotechnology, Jawaharlal Nehru Technological University (JNTU), Hyderabad, TS, India
  • Rao AV Center for Cellular & Molecular Biology (CSIR-CCMB), Hyderabad, India
  • Ravindra Babu Potti Department of Biotechnology, Sree Nidhi Institute of Science Technology, Hyderabad, India
  • Murty KVGS Varun Herbals-DSIR-SIRO (Scientific & Industrial Research Organization), Ministry of Science& Technology, Govt of India

Abstract

Continued oxidative stress can lead to chronic inflammation, which in turn could mediate most chronic diseases including cancer, diabetes, and cardiovascular, neurological and pulmonary diseases. Oxidation should be arrested in the cells as it leads to chain reactions followed by cell damage. Inflammation induces various chemicals due to which redness and warmth appear at the site of inflammation. Current treatment packages available in the market which may be of allopathic or nutritional are unable to control the mortality of cancer. On the contrary allopathic leads to side effects and increasing the risk of the patient, so there is an immense need for other treatment cum management packages are to be explored in particular from medicinal plants. Jatamansi (Nardostachys Jatamansi) appears to be one of the prospective herbal single drugs which can address oxidative stress and inflammatory situations. Jatmansi showed encouraging anti-inflammatory activity and antioxidant activity, thereby being a small study, future investigation of Nardostachys Jatamansi extract required for better understanding the molecular mechanism is yet to be performed.

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Published
2018-10-30
How to Cite
I, Rajyalakshmi et al. Effects of Nardostachys jatamansi extract on inflammatory and oxidative stress markers in hypertensive, hyperglycaemic patients: an open-label, prospective study. International Journal of Research in Pharmaceutical Sciences, [S.l.], v. 9, n. 4, p. 1096-1098, oct. 2018. ISSN 0975-7538. Available at: <https://pharmascope.org/index.php/ijrps/article/view/1637>. Date accessed: 12 dec. 2018. doi: https://doi.org/10.26452/ijrps.v9i4.1637.
Section
Original Articles
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