Role of nutrition in rehabilitation of patients following surgery for oral squamous cell carcinoma

  • Mahathi Neralla Department of Oncology, Oral Cancer Institute, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Jones Jayabalan Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Rinku George Department of Oncology, Oral Cancer Institute, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Jyotsna Rajan Department of Oncology, Oral Cancer Institute, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Santhosh Kumar M.P Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Ahmed Elham Haque Department of Oncology, Oral Cancer Institute, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Arthi Balasubramaniam Department of Community Dentistry, Saveetha Dental College and Hospital, Chennai-600077, Tamil Nadu, India
  • Pradeep J. Christopher Department of Oral and Maxillofacial Surgery, Thai Moogambigai Dental College and Hospital, Chennai-600037, Tamil Nadu, India

Abstract

Malnutrition in oral cancer patients leads to poor response to treatment and reduced quality of life. The present study assessed the nutritional status of patients treated for oral squamous cell carcinoma and evaluated the need for implementation of any institutional protocol regarding the type of nutritional intervention employed for these patients. Patients with oral squamous cell carcinoma who had undergone primary tumor resection with or without neck dissection and reconstruction from June 2015 to June 2018 were evaluated. Of the patients with complete data recalled for review, only 25 reported to our Institute, including 12 who had undergone surgery alone and 13 who had undergone surgery plus adjuvant radio and/or chemotherapy. Their nutritional status was assessed by measuring their Mini Nutritional Assessment (MNA) scores, and MNA scores in the groups that underwent surgery alone and surgery plus adjuvant therapy compared by independent sample ‘t’ tests. Of the 12 patients who underwent surgery alone, eight had normal nutritional status, and four were at risk of malnutrition. Of the 13 patients who underwent surgery plus adjuvant therapy, only one had normal nutritional status, whereas 12 were at risk of malnutrition or malnourished. Mean MNA score was significantly higher in patients who had undergone surgery alone than in patients who had undergone surgery plus adjuvant therapy (p=.001). Risk of malnutrition was higher in patients who underwent surgery plus adjuvant therapy than in patients who underwent surgery alone. Postoperative care of patients with oral squamous cell carcinoma should include nutritional management to improve patient prognosis and quality of life.

Keywords: Cachexia, Head and neck cancer, Malnutrition, Mini nutritional assessment, Oral cancer, Weight loss

Downloads

Download data is not yet available.
Published
2019-10-16
Citations
How to Cite
Mahathi Neralla, Jones Jayabalan, Rinku George, Jyotsna Rajan, Santhosh Kumar M.P, Ahmed Elham Haque, Arthi Balasubramaniam, & Pradeep J. Christopher. (2019). Role of nutrition in rehabilitation of patients following surgery for oral squamous cell carcinoma. International Journal of Research in Pharmaceutical Sciences, 10(4), 3197-3203. https://doi.org/10.26452/ijrps.v10i4.1622
Section
Original Articles
Article Level Metrix
Abstract Views: 40
PDF Downloaded: 20           LaTeX Downloaded: 4           HTML Downloaded: 1           ePUB Downloaded: 3