Synthesis and characterization Some of heterocyclic compounds from Nitrogen derivative

  • Sarah Mohammed Abed Faculty of Education for Girls, University of Kufa, Iraq
  • Hasan Thamer Ghanem Faculty of Education for Girls, University of Kufa, Iraq

Abstract

This paper involves the synthesis of new oxazepine derivatives by multi-reaction steps. The first step synthesis azo derivative from 2-naphthol with 3-aminoacetophenone. The second step was the condensation reaction between ketone group of the azo compound and different primary aromatic amines (4-amino phenol, 3-nitro aniline and 4-methyl aniline) to yiled new azo Schiff base compounds (S1-S3) respectively. In the final step, Oxazepine compounds (L1-L3)and (L4-L6)were prepared from reaction imine compounds (S1-S3) with maleic and phthalic anhydride in toluene as solvent. All these derivatives were characterized by melting point, FTIR, HNMR and 13CNMR.

Keywords: Azo compounds, multi-reaction steps, Schiff bases, Oxazepine

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Published
2019-10-16
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How to Cite
Sarah Mohammed Abed, & Hasan Thamer Ghanem. (2019). Synthesis and characterization Some of heterocyclic compounds from Nitrogen derivative. International Journal of Research in Pharmaceutical Sciences, 10(4), 3186-3196. https://doi.org/10.26452/ijrps.v10i4.1621
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Original Articles
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