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India is a country with different beliefs like religious, cultural, variation and economic diversity in the health care setting. SLE is a long term disease which involves multisystem, leading to loss of immune tolerance to own antigens. The study aims to assess the knowledge regarding the risk of cardiovascular diseases among systemic lupus erythematous patient at Saveetha Medical College and Hospital. A quantitative research approach was adopted with convenient sampling technique to select 60 patients with systemic lupus erythematosus who attend at Saveetha Medical College and Hospital. Data was collected using a semi-structured questionnaire. The data was organized and analyzed in term of descriptive statistics. The study findings revealed that among 60 samples, 10 (16.7%) had inadequate knowledge; 16 (26.7%) had moderate knowledge, 34 (56.7%) had adequate knowledge on systemic lupus erythematous risk. The majority of the patients with systemic lupus erythematous had moderate knowledge regarding the risk of cardiovascular.
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