Drug utilisation pattern and risk factor assessment on abnormal uterine bleeding in reproductive aged women in a tertiary care hospital

  • Kothai Ramalingam Department of Pharmacy Practice, Vinayaka Mission’s College of Pharmacy Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India
  • Atheena Gigi Department of Pharmacy Practice, Vinayaka Mission’s College of Pharmacy Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India
  • Anu Sara Thomas Department of Pharmacy Practice, Vinayaka Mission’s College of Pharmacy Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India
  • Abdul Mohsin Mootaparambil Department of Pharmacy Practice, Vinayaka Mission’s College of Pharmacy Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India
  • Arul Balasubramanian Department of Pharmacy Practice, Vinayaka Mission’s College of Pharmacy Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India

Abstract

To study the drug utilization pattern and risk factor assessment on abnormal uterine bleeding in reproductive-aged women in a tertiary care hospital at Salem district, Tamil Nadu, India. This retrospective study was carried out for a period of 6 months from November 2017 to April 2018 in which 150 prescriptions were selected for study by considering the inclusion and exclusion criteria. A total of 150 prescriptions were analyzed in reproductive-aged women. Patients of age group between 41-50 years were mostly diagnosed 75 (50%) of abnormal uterine bleeding. Considering the types of AUB, most of the patients (39.33%) which has been diagnosed as adenomyosis while 59 (32.67%) of the patient has been diagnosed leiomyoma 49 (32.67%). Anaemia 102 (68%) are the most seen co-morbid condition in our survey, along with Hypertension 28 (18.6%), Infective disorders 28 (18.6%). Our findings showed that among the drugs prescribed, that antifibrinolytics were the most often prescribed drug class for AUB, and the most prescribed drug is tranexamic acid. Perimenopause 57 (38%) is the main risk factor in abnormal uterine bleeding, along with dysfunctional uterine bleeding 47 (32.6%). From we concluded that The mostly used class of drug for abnormal uterine bleeding in our tertiary care hospital is antifibrinolytics and mostly used drug agent is tranexamic acid during the period of data collection. It is found to be that perimenopause is the main risk factor in abnormal uterine bleeding along with dysfunctional uterine bleeding.

Keywords: Abnormal uterine bleeding, Tranexamic acid, Perimenopause, Drug utilization review, Risk factors

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Published
2019-10-16
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How to Cite
Kothai Ramalingam, Atheena Gigi, Anu Sara Thomas, Abdul Mohsin Mootaparambil, & Arul Balasubramanian. (2019). Drug utilisation pattern and risk factor assessment on abnormal uterine bleeding in reproductive aged women in a tertiary care hospital. International Journal of Research in Pharmaceutical Sciences, 10(4), 2687-2690. https://doi.org/10.26452/ijrps.v10i4.1529
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Original Articles
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