Spectrophotometric estimation of Nifidipine by using various solvents

  • AlagarRaja M Department of pharmaceutical analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
  • Selva Kumar D Arya Vaidhya Nilayam, Madurai, Tamilnadu, India
  • Muthu Kumar S Department of pharmaceutical analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
  • Purnima Tripathi Department of pharmaceutical analysis, Kamla Nehru Institute of Management & Technology, Faculty of Pharmacy, Faridipur, Sultanpur, Uttar Pradesh, India
  • Amuthadevi C Ultra college of Pharmacy, Madurai, Tamilnadu, India

Abstract

A Simple and sensitive spectrophotometric method has been developed for the estimation of nifedipine in bulk and tablet formulation. The drug was determined by using various solvents like aqueous, organic and inorganic, which is determined spectrophotometrically at 281nm. The percentage recovery study of the drug for the proposed method range from 98-102% indicating no interference of the tablet excipients by using various solvents. The result obtained for percentage purity of nifidipine was dimethyl formamide and glacial acetic acid was only the solvents indicating the limit of recovery studies.

Keywords: Nifidipine, dimethyl formamide, glacial acetic acid

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Published
2010-01-05
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How to Cite
AlagarRaja M, Selva Kumar D, Muthu Kumar S, Purnima Tripathi, & Amuthadevi C. (2010). Spectrophotometric estimation of Nifidipine by using various solvents. International Journal of Research in Pharmaceutical Sciences, 1(1). Retrieved from https://pharmascope.org/index.php/ijrps/article/view/137
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