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Cancer is rated as one of the most dreadful diseases next to AIDS. Breast cancer has emerged as the leading site of cancer among women and has overtaken cancer of the uterine cervix. The aim of the study was to find out mineral status in plasma and tissue of the breast cancer patients compared to healthy subject and minerals selected for the study were calcium, phosphorous, iron, copper and chlorine. In breast cancer condition, calcium, phosphorous and iron levels were significantly increased and decreased copper and chlorine levels in both tissue and plasma were observed. Present study results showed that the minerals could be used as diagnostic tool for breast cancer patients. It was concluded that copper and chlorine supplementation might lower risk of breast cancer patients.