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Abstract

The anti-inflammatory effect of the Pet ether and aqueous leaf extract of Parkinsonia acculeata was evaluated using the carrageenan and formalin induced rat paw edema. The extract administered orally at 500 mg/kg b. w produced a significant inhibition. The results obtained suggest that the Pet ether and aqueous leaf extract of Parkinsonia acculeata is endowed with effective anti-inflammatory activity mediated via either inhibition of cyclo-oxygenase pathways, inhibiting the synthesis of inflammatory mediators and scavenging free oxygen radicals. These findings seem to justify that the plant can be used as an anti-inflammatory agent.  

Keywords

Parkinsonia acculeata Carrageenan formalin anti-inflammatory

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How to Cite
Ghalib I. Hundekari, Shukoor M. A, Nagappa A. N, Syeda Shahana, Syeda Saba, & Shaikh Samina. (2012). Anti inflammatory activity of Parkinsonia acculeata on carrageenan and formalin induced rat paw edema in rats. International Journal of Research in Pharmaceutical Sciences, 3(3), 410-413. Retrieved from https://pharmascope.org/ijrps/article/view/1055