Anti-nociceptive activity of ethanolic extract of Spermacoce hispida L.

  • Sundhararajan R Vels College of pharmacy, Velan Nagar, Pallavaram, Chennai - 600 117, Tamil Nadu, India
  • Ravichandiran V Vels College of pharmacy, Velan Nagar, Pallavaram, Chennai - 600 117, Tamil Nadu, India

Abstract

The plant Spermacoce hispida Linn (Rubiaceae) commonly known as Shaggy button weed or jointed button weed is been in practice as a traditional medicine for various disorders. In order to document the traditional wisdom on the plant the present study was aimed evaluate the antinociceptive activity of the ethanolic extract of Spermacoce hispida (SHE) employing the acetic acid-induced abdominal constrictions and Tail immersion models. SHE (200mg/kg), showed significant analgesic or antinociceptive potential when compared to that of the standard drug Aspirin 100 mg/kg. and Pentazocine 5 mg/kg respectively.

Keywords: Spermacoce hispida, analgesia, antinociceptive activity

Downloads

Download data is not yet available.
Published
2012-01-25
Citations
How to Cite
Sundhararajan R, & Ravichandiran V. (2012). Anti-nociceptive activity of ethanolic extract of Spermacoce hispida L. International Journal of Research in Pharmaceutical Sciences, 3(1), 173-175. Retrieved from https://pharmascope.org/index.php/ijrps/article/view/1014
Section
Original Articles
Article Level Metrix
Abstract Views: 4
PDF Downloaded: 9