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Multidrug-resistant (MDR) organisms become a foremost health concern in both developing and developed countries. These infectious agents show a wide spectrum of resistance against different antimicrobial drugs which causes a major public health threat all over the world. In recent years bacteria, fungi, virus, and parasites started to show prominent levels of multidrug-resistance with superior morbidity and mortality. MDR Salmonellosis requires costly drugs for effective treatment, and this is an added burden to the health-care segment in developing countries. Immunization in common areas with typhoid vaccine, rational use of antibiotic, improvement in public sanitation facilities, secure food handling and communal health instruction were considered to be as vital in the prevention of salmonellosis. These health and environmental issues require collective actions from governments, consumers, pharmaceutical manufacturers and health-care providers. Two methods were followed to congregate the information in this article. Firstly, we collected a list of relevant articles published through PubMed search, which includes original as well review articles. Secondly, book chapters on typhoid fever from standard textbooks on infectious diseases and social remedy were also reviewed.


Fluoroquinolone treatment Multidrug-resistance Plasmid & chromoso-mal mediated re-sistance Salmonellosis Typhoid vaccine

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How to Cite
Balasubramani Gangathraprabhu, Santhanam Geethanjali, Nagarethinam Baskaran, & Marudhamuthu Murugan. (2019). Multidrug-resistant Salmonella: A raising calamity . International Journal of Research in Pharmaceutical Sciences, 10(1), 318-327. Retrieved from