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The current study was undertaken to analyze the bacteriological profile among diabetic foot ulcer patients and to determine the antibiotic susceptibility and resistance pattern of the organisms isolated. This was a prospective observational study conducted among 102 patients for six months. All patients, aged above 18 years diagnosed with diabetic foot ulcers and performed with culture and sensitivity tests in the department of general surgery, were enrolled in the study. All the relevant details of the study were collected and analyzed. Out of 102 patients enrolled, 72 were males and 30 were females. The majority of the bacteria that were isolated from the culture samples were found to be gram-negative, 119 (79.33%) and 31 (20.97%) were found to be gram-positive. Methicillin-resistant coagulase-negative Staphylococcus was the most frequently isolated gram-positive micro-organism. It was found to have more sensitivity to both vancomycin and teicoplanin (100%) whereas it showed high resistance to benzylpenicillin (84.6%). Among various gram-negative organisms, Pseudomonas aeruginosa was the most commonly isolated. It showed high sensitivity to doripenem (70.9%) and was found to be more resistant to levofloxacin (51.6%). Our study concluded on the predominance of gram-negative bacteria among the enrolled patients. Among the 22 different types of bacteria identified, Pseudomonas aeruginosa was the most frequently isolated species.


Diabetes diabetic complication antibiotics bacterial resistance ulcer antibiotic susceptibility

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Steffy Ligi Binu, Abhishek Chandran, Chaitrashree, Abhijith Shetty, Sharad Chand, Juno J. Joel, Bharath Raj K C, & Nandakumar U P. (2021). Bacterial Profile and Antibiotic Susceptibility Pattern among Diabetic Foot Ulcer Patients. International Journal of Research in Pharmaceutical Sciences, 12(1), 160-168.