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Abstract

Nanotechnology has become one among the promising approaches for innovations which fulfil the human needs. Nanoparticles even have many applications in several fields like nanocomposites, medical imaging, nanobiocomposite filters, targeted drug delivery and hyperthermia of tumours. In which Selenium is an important micronutrient for living organisms. These nanoparticles are safe, eco friendly, inexpensive and nontoxic. Enterococcus faecalis  is an emergent gram - positive opportunistic pathogen that is the causative agent of several nosocomial infections and surgical wound infections. Therefore, it is becoming increasingly necessary to find other alternative treatments than commonly utilized drugs. The purpose of this study is to assess the antibacterial activity of Capparis decidua  fruit mediated selenium nanoparticles( cds-se Nps ) against Enterococcus faecalis. In this experimental study Se Nps were prepared by the reaction of 30mM sodium selenite solution and extracts of Capparis decidua. Antibacterial activity of SeNPs was assessed by using a disc diffusion method against Enterococcus faecalis. The SeNPs were characterized by UV-visible spectrophotometers. In the present study, the zone of inhibition shows 32mm, 35 mm, 37mm and 30 mm at concentration of 50 microliter, 100 microliter, 150 microliter and antibody respectively. The Capparis decidua  fruit mediated SeNp showed a good antibacterial activity against the pathogen Enterococcus faecalis 

Keywords

Capparis decidua Selenium nanoparticle Antibacterial activity Enterococcus faecalis

Article Details

How to Cite
Anushya P, Preetha S, Lavanya Prathap, & Jeevitha M. (2021). Enhanced Antibacterial activity of Capparis decidua fruit mediated Selenium Nanoparticle against Enterococcus faecalis. International Journal of Research in Pharmaceutical Sciences, 12(1), 6-11. https://doi.org/10.26452/ijrps.v12i1.3905