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Abstract

In recent days, threat related to infectious and antibiotic-resistant pathogens are increasing widely, and this created an urge to search for an alternative way of producing drugs. The sources selected for the production of drugs must have some attributes like readily available, available in bulk quantities, easy processing and containing less or negligible toxic effects. Herbal medications and drugs derived from medicinal plants may serve as a smart and an alternate way. In this study, ethanolic seed extracts have been used from three readily available plants like Cucumis sativus  L., Carica papaya  L., Annona squamosa  L. The antibacterial activity of ethanolic seed extracts was performed against the pathogens present in the pus sample using agar disc diffusion method. It was found that the ethanolic seed extracts of Cucumis sativus L. were found to have a maximum zone of inhibition of 14 mm at conc., of 900 µg against S. aureus, Carica papaya L. was found to have maximum inhibition of 13mm at conc., of 900µg against S. aureus and Annona squamosa showed negligible resistance to all pus pathogens. From the various bioactive compounds present in the plants, an efficient drug can be manufactured, and it may find a great place in the pharmaceutical industry. 

Keywords

Anti-microbial activity Antibiotic resistance Cucumis sativus L. Carica papaya L. Annona squamosa L.

Article Details

How to Cite
Abirami S, Antony V Samrot, Emilin Renitta R, Kanchana S, Noorudeen M B, Yamunadevi K, Dhiva S, & Saigeetha S. (2020). Anti-microbial activity of seed extract of Cucumis sativus L., Carica papaya L. and Annona squamosa L. International Journal of Research in Pharmaceutical Sciences, 11(4), 6719-6726. https://doi.org/10.26452/ijrps.v11i4.3603