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Crohn’s disease (CD) is a lifelong debilitating condition. Different theories have been proposed regarding the aetiology of the disease like genetic factors, microbial factors and in recent years there is increased interest in the role of Mycobacterium in this disease. The high global incidence of this disease has been reported. The disease was rare till 1980s in India, however, past few decades has seen an increased prevalence. Presently available treatment offers symptomatic relief. Surgery is suggested in advance cases. However, frequent relapses of the disease have been observed. Therefore, therapeutic development for CD is a hot area of research and many new avenues are being explored. Here we review the classical and modern advances in managing this disease.


Crohn’s disease Chemotherapy Immuno-suppression Immuno-modulation

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Sujata Jayaraman, Mukta Jain, Amit Kumar Singh, Aseri GK, Parul Yadav, Neeraj Khare, Deepansh Sharma, & Jagdip Singh Sohal. (2018). Crohn’s Disease Management: From Classical Approaches to Recent Ad-vances. International Journal of Research in Pharmaceutical Sciences, 9(3), 1002-1015. Retrieved from