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The present study to investigate the extent of use of misoprostol in postpartum hemorrhage. To evaluate the knowledge of prevention and treatment of managing PPH among health care providers. To educate the pregnant women and midwives on the treatment approaches for PPH. The present study was conducted in RVS Institute of Medical Sciences, Chittoor, Andhra Pradesh. In the wards of obstetrics and gynecology, especially in the postnatal ward. The materials required for the study are collected from the gynecology and obstetrics department of the hospital included in the study. The study details with all the details of aim, objective, methodology, inclusion criteria, exclusion criteria, expected outcome have been submitted to the ethical committee, and after getting a positive opinion from the institution ethics committee(IEC) towards the study, the work has been started. The study included about 316 maternal women. All the women included in the study have been administered with Misoprostol after giving birth to the neonate to prevent the occurrence of atonic PPH, which is the most widely seen complication resulting in birth of maternal women.The common side effects observed in the maternal women were vomiting, which was reported in 27 women out of 316 women. Diarrhea was reported in 12 women out of all study population. Shivering was accounted in 167 women, thus, shivering is the major side effect noted with administration of misoprostol. One women was reported with an elevated diastolic blood pressure of >100 mm of Hg out of 316 women. Manual removal of placenta was necessitated in 19 women. Misoprostol was administered in all the women (n = 316) after 4- 5 hours of delivery. However, it’s needed to increase the mandatory guidelines for management of various complications accounted during delivery to prevent maternal mortality rate.
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