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The sustained release system is formulated to release a drug slowly over a period of time in the body. The sustained release system is having more therapeutic activity of a drug when compared to immediate release. Beads is one of the most commonly used technique in a sustained release dosage form. These are the spherical particle with size ranging from 50nm to 2mm, which contains core substances. The molecular size of the drug particle must be lesser than 1000 Dalton to formulate as SRDF. This article also contains the method of preparation by the emulsion cross-linking method. The ionic gelation process used calcium chloride as a crosslinking agent to successfully produce alginate beads. It is concluded that the release of spores and metaloxyl from the beads was controllable and sustainable, which is essential to the environment and ecosystem in the biocontrol of aflatoxin and pesticide management. The drug-like acetazolamide is prepared by using calcium alginate, and glipizide beads is coating is explained. Information about iron cross-linked carboxymethyl cellulose gelatin coacervate beads is mentioned, a brief explanation about the oyster hydrolysate containing in liposome in alginate beads is given. Then ofloxacin interpenetrating polymer beads to taste masking for sustained release information is added. The present sustained-release beads in the market is included.
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