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The experiment was designed to investigate the impact of tuberculosis in patients with the disease. This cross-sectional study was performed in Al-Qadisiyah province, Iraq. This examination was conducted with 60 males that age ranges from 25-55 years, which divided into 30 males with Tuberculosis disease and 30 voluntaries healthy as a control group. Assay of study evaluation of parameters levels that include: Bodyweight Albumin, total protein, AST, ALT, urea and creatinine, ESR, Hb, and WBC count. Also, the study included Zn estimation by using solid-phase enzyme-linked immunosorbent assay.
The results reported a significant (P<0.05) decreased in biochemical investigation in this study (Bodyweight, albumin, total protein, and ALT) while the hematological analysis showed substantial decreased in Hb but exhibited a significant (P<0.05) increases in ESR and WBC count in male's patients with Tuberculosis disease as compared with healthy groups. Although, the result showed significant (P<0.05) decreased in Zn level in a patient with Tuberculosis compared with control, While AST doesn't show significant (P<0.05) compared with control. Urea and Creatinine levels were significantly decreased in patients Tuberculosis disease compared with control healthy.
The current study concluded that tuberculosis disease affected the liver and kidney by decreasing the protein and enzyme produced in the liver, and the kidney also causes a defect in hematological parameters in patients with the disease.
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