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This paper involves the synthesis of new oxazepine derivatives by multi-reaction steps. The first step synthesis azo derivative from 2-naphthol with 3-aminoacetophenone. The second step was the condensation reaction between ketone group of the azo compound and different primary aromatic amines (4-amino phenol, 3-nitro aniline and 4-methyl aniline) to yiled new azo Schiff base compounds (S1-S3) respectively. In the final step, Oxazepine compounds (L1-L3)and (L4-L6)were prepared from reaction imine compounds (S1-S3) with maleic and phthalic anhydride in toluene as solvent. All these derivatives were characterized by melting point, FTIR, HNMR and 13CNMR.


Azo compounds multi-reaction steps Schiff bases Oxazepine

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How to Cite
Sarah Mohammed Abed, & Hasan Thamer Ghanem. (2019). Synthesis and characterization Some of heterocyclic compounds from Nitrogen derivative. International Journal of Research in Pharmaceutical Sciences, 10(4), 3186-3196.