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There are many reports proved great potential effects of curcumin in various diseases. Curcumin exhibits antioxidant, anti inflammation, antimicrobial and anticarcinogenic activities. It’s unique ability to work through so many different pathways has a positive influence in combating almost every known disease. However, lack of its stability and solubility limits its therapeutic applications in clinic. Several approaches have been described not only in chemical modifications but also in formulation technologies to expose the therapeutic values of curcumin. This review presented an updated concise review of currently available technologies to improve the physicochemical characteristic of curcumin as well as its stability, hence showing better therapeutic effects, using different types of nanoform: nanocrystal and nanocarriers.
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