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Abstract

Some Schiff base metal complexes of Co(II), Ni(II) and Cu(II) derived from 2-thiophenecarboxaldehyde with 2-imidodicarbonic diamide (TID) 2-chloro-4-nitroaniline (TCA) have been synthesized and characterized by elemental analysis, FT-IR, molar conductance, electronic spectra, ESR, magnetic susceptibility, and thermal analysis. The complexes exhibit coordination number 4 or 6. The complexes are coloured and stable in air. Analytical data revealed that all the complexes exhibited 1:1 or 1:2 (metal: ligand) ratio. Thermal data show degradation pattern of the complexes. The Schiff base and metal complexes show a good activity against the Gram-positive bacteria; Staphylococcus aureus and Gram-negative bacteria; Escherichia coli and fungi Aspergillus niger and Candida albicans. The antimicrobial results also indicate that the metal complexes are better antimicrobial agents as compared to the Schiff bases.

Keywords

Synthesis 2-Thiophenecarboxaldehyde Thermal analyses Biological activity

Article Details

How to Cite
Mishra AP, Annapoorna Tiwari, & Rajendra Jain. (2012). Synthesis, spectral, thermal and antimicrobial studies of some transition met-al complexes containing 2-thiophenecarboxaldehyde moiety. International Journal of Research in Pharmaceutical Sciences, 3(2), 186-191. Retrieved from https://pharmascope.org/ijrps/article/view/1018