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The anti bacterial activity of ethanolic extract and its bioactivite guided fraction of the seaweed Acanthophora spicifera (ACS) was studied by disc diffusion method using Muller Hinton agar medium and the zone of inhibition was compared that of standard ciprofloxacin (5µg/ disc). All the tested extract and guided fractions showed potential antibacterial activity to that of the standard drug against the tested organisms. The MIC for all the test samples was fixed at 300 µg/ml. Hence the presence study validated the scientific documentation of the anti infective property of the seaweed ACS.
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